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“WHERE THINGS SO SMALL CAN HAVE A MASSIVE IMPACT ON YOUR HEALTH.”
Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

Nuts about walnuts? It’s a good thing

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Nuts about waln...
Did you notice walnuts look like the brain? That’s because they’re good for the brain and not because they have the physical characteristics of a human brain but because they have the most omega-3 fatty acids of all the nuts, according to Facty.

But that’s not it. Walnuts have more good fatty acids, for heart health such as monounsaturated fatty acids. Walnuts contain healthy fatty acids like oleic acid and linoleic acid which can aide in reducing bad LDL cholesterol and increasing good HDL (high density lipoproteins) cholesterol; “the good cholesterol “ which removes harmful LDL cholesterol, as explained by Webmd (2).

https://facty.com/food/nutrition/the-delicious-health-benefits-of-walnuts/

2. https://www.webmd.com/cholesterol-management/guide/hdl-cholesterol-the-good-cholesterol

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Human microbiome market to become $1.37 billion by 2029

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Taking a break from science, what about the economics of our gut microbiome? According to a Digital Journal article reporting on MarketsandMarkets™, the global human microbiome market is projected to reach USD 1.37 billion by 2029 from USD 269 million in 2023, at a CAGR of 31.1% from 2023 to 2029.

The report says the growth is largely due to growth in gut microbiome treatment and drug development. Digital Journal reports that the Asia Pacific region is the fastest-growing region of human microbiome research spending market from 2023 to 2029.

https://www.digitaljournal.com/pr/human-microbiome-market-worth-1370-million-by-2029-global-trends-share-and-leading-key-players

Download PDF Brochure: https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=37621904

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Our gut microbiome contributes to cravings

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Diet preference and our gut m... Diet preference and our gut microbiome.

image source: dreamstime.com
According to an April 26 2022 Medical News Today report, microbes contribute to our cravings and play a major role in our processing of nutrients.

These are based on mice studies by Dr. Kevin Kohl, assistant professor in the Department of Biology at the Kenneth P. Dietrich School of Arts and Sciences at the University of Pittsburgh and Dr. Trevelline, Rose postdoctoral fellow at the Cornell Lab of Ornithology.

Dr. Trevelline said the microbes in the gut were beneficial contributors to a lot of processes, particularly by synthesizing the nutrients humans need and supplementing our diets.

Their research showed that the mice that received diverse types of microbiota voluntarily changed their diet preferences. “Our work shows that animals with different compositions of gut microbes choose different kinds of diets,” Dr. Kohl said.

Drs. Trevelline and Kohl also discovered that that varying levels of tryptophan in mice’s blood led to their choosing different diets, according to the Medical News Today article.

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MIT develops bacteria that breaks down antibiotics

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source: dreamstime.com source: dreamstime.com
MIT News reported April 11 2022 that MIT researchers successfully engineered a bacteria based antibiotic treatment. The enzyme of this bacteria can help reduce the risk of inflammation caused by antibiotics.

MIT engineers developed a strain of bacteria that is safe for human consumption that safely produces an enzyme that breaks down a class of antibiotics called beta-lactams. These include ampicillin, amoxicillin, and other commonly used drugs, according to the MIT News article.

James Collins, the Termeer Professor of Medical Engineering and Science in MIT’s Institute for Medical Engineering and Science (IMES) and Department of Biological Engineering, and the senior author of the new study, refers to this application as “living biotherapeutics”.

https://news.mit.edu/2022/bacteria-good-gut-microbes-antibiotics-0411

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Researchers near replicating carbon reduction process in nature

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source: dreamstime.com source: dreamstime.com
Researchers found that enzymes from certain bacteria in the soil turns carbon dioxide in the air into carbon molecules, a process that helps reduce the carbon footprint which drives climate change.

An international consortium of university researchers including Stanford’s Department of Energy’s SLAC National Accelerator Laboratory have figured out a way to potentially artificially duplicate the process in lab, according to an April 29 2022 report by Glennda Chui of the Stanford National Accelerator Lab.

The process known as carbon fixing, is the key component in photosynthesis. But instead of a 20 times slower process in plants, the soil bacteria, Kitasatospora setae, relies on enzymes called Rubisco. Researchers also found it can also produce antibiotics, according to Chui’s article quoting Soichi Wakatsuki, a professor at SLAC and Stanford.

The next step will be to build on an enhanced version of the artificial process.

https://www6.slac.stanford.edu/news/2022-04-29-how-soil-microbe-could-rev-artificial-photosynthesis.aspx

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Cayenne pepper helps to diversify microbiome community

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source: dreamstime.com source: dreamstime.com
On April 19 2022 Mind Body Green reported a study that found "that capsaicin (in cayenne pepper) alters the gut microbial community structure by increasing the diversity of the community." Capsaicin is an antioxidant said to aid in proper digestion, with anti-inflammatory effects. Researchers used the in vitro model to conduct their research.

Capsaicin stimulates the nerves in your stomach and us said to help to increase the production of digestive fluid. According to WebMD, it sends enzymes to the stomach to aid in digestion, and protectshe the stomach from infections.

https://amp.mindbodygreen.com/articles/capsaicin-gut-health-study
#bacteria #datascience #gutmicrobiome #health #healthinnovation #wellness

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anti-inflammatory effects of certain viruses

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Dr. Kate. L. Jeffrey, associate professor of medicine at Harvard Medical School, isolated viruses from a patient’s colon surgical tissue, and found that viruses in a normal intestine had anti-inflammatory effects and contributed to a healthy gut.

Dr. Jeffrey isolated some viruses in the gut of their patients and found that these viruses in a "normal intestine had anti-inflammatory effects and contributed to a healthy gut." Other viruses had the opposite effect, thus calling for a viral balance.

Other researchers studied mice that were given viruses from healthy human colons and found they were protected from intestinal inflammation. Conversely, mice whose intestinal viruses were replaced with viruses associated with IBD exhibited exacerbated inflammation.

https://medicalxpress.com/news/2022-04-gut-viruses-intestinal-health-contribute.amp

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Urolithin A said to reduce aging

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source: dreamstime.com source: dreamstime.com
According to Popular Science, researchers at the Swiss Federal Institute of Technology Lausanne (EPFL) and life-science company Amazentis believe they have found a way to reduce muscle decline and low energy with a highly pure Urolithin A supplement. Gut bacteria generate urolithin A from pomegranates, berries, and nuts.

Mitochondria which converts food into energy, generates adenosine triphosphate (ATP) life-sustaining chemical tissue, and mitophagy which is the process of breaking down old worn out mitochondria. The March 22 2022 Popular Science report says researchers found that Urolithin A boosts mitophagy. It is produced as a by-product when gut bacteria digest specific ingredients such as pomegranates (1).

David Marcinek, Ph.D., a professor of radiology at the University of Washington School of Medicine in Seattlein Medicine News Today, believes that Urolithin A supplements may provide a way to stimulate mitophagy in older people and help them maintain strength and endurance. He and his team are doing preliminary clinical trial to find out the efficacy and safety of such supplements (2).

https://www.popsci.com/sponsored-post/scientists-in-switzerland-discover-that-gut-microbiome-postbiotic-urolithin-a-may-help-combat-muscle-fatigue-with-aging/

https://www.medicalnewstoday.com/articles/gut-microbiome-may-hold-key-to-combat-muscle-decline-in-aging

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Gut microbiome linked to cognitive aging

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source: dreamstime.com source: dreamstime.com
According to a February 22, 2022 Medical News Today report, researchers from the United States analyzed data from a large cross-sectional study of CARDIA, Coronary Artery Risk Development, in Young Adults and found a link between gut microbial composition and cognitive status in middle-aged adults.

607 stool samples were studied for DNA sequencing of adults across the country with a mean age of 55. The genera Barnesiella, Lachnospiraceae, and Akkermansia were positively associated with at least one of the cognitive tests, while Sutterella was negatively associated with one test.

Scientists believe that short-chain fatty acids play a part in regulating how the gut and brain interact. Short-chain fatty acids have been associated with protection against vascular dementia and cognitive impairment, according to the Medical News Today article.

https://www.medicalnewstoday.com/articles/microorganisms-in-the-gut-are-linked-to-cognitive-function

Related news: https://www.the-scientist.com/news-opinion/bacteria-infecting-viruses-in-gut-microbiome-linked-to-cognition-69709

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gut bacteria reduces productivity as we age

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source: dreamstime.com source: dreamstime.com
According to a January 25, 2022 Medical News Today report, gut bacteria which produce a metabolite called urolithin A improves the overall efficiency of mitochondria, which prevent fatigue and helps maintain strength and endurance.

Part of the issue is that as we age, our cells progressively lose their capacity for “mitophagy”, which is the breakdown and recycling of faulty mitochondria, says David Marcinek, Ph.D., a professor of radiology at the University of Washington School of Medicine in Seattle. Professor Marcinek and his team are currently exploring clinical trials of Urolithin A supplements to determine efficacy for the aging.

https://www.medicalnewstoday.com/articles/gut-microbiome-may-hold-key-to-combat-muscle-decline-in-aging
Would you use Urolithin A supplements if it were safe and available?

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