記事検索

Herbsprout.com

https://jp.bloguru.com/healthtech

フリースペース

“WHERE THINGS SO SMALL CAN HAVE A MASSIVE IMPACT ON YOUR HEALTH.”
Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

large African study reveals gut diversity and health

スレッド
large African study reveals gu...

Researchers discovered new microbial species and never-before-reported metagenomes from several African sites, according to Professor Scott Hazelhurst, senior scientist at the Sydney Brenner Institute for Molecular Bioscience (SBIMB) and Professor of Bioinformatics, Wits University, as reported in a January 30 2025 issue of Phys.org. The study adds high-quality genomes of 1,005 bacterial and 40,135 viral species.
 
We now know that geography largely shapes microbiome differences, with some species thriving in rural areas and others in industrialized settings,” says co-author Dr. Luicer Ingasia Olubayo of the SBIMB as quoted in the Phys.org report.
 
The study identified “food deserts” where there is a gross deficiency of healthier fresh produce and foods. In addition, there is the absence of important bacteria, Treponema, in urban participants. The study found that people living in food deserts have a “higher risk of developing diabetes, heart disease, and obesity.”
 

ワオ!と言っているユーザー

gut microbe found to produce anxiety regulating indoles

スレッド
gut microbe found to produce ...
Researchers have discovered that naturally occurring gut microbes produce indoles—compounds that play a key role in regulating anxiety-related brain activity, according to a February 17 2025 SciTech Daily report. Many gut microbes produce indole, including Escherichia coli, Bacteroides,Clostridium, Bifidobacterium, and Lactobacillus.
 
This discovery is based on research by scientists at Duke-NUS Medical School and the National Neuroscience Institute in their newly published study in EMBO Molecular Medicine. The basolateral amygdala (BLA) is the brain region that processes emotions such as fear and anxiety.
 
The study found that the when the body and brain are exposed to live microbe metabolites, the SK2 channels prevent neurons from over-excitement, according to Sci-Tech Daily.
 
Professor Sven Pettersen, Singapore National Neuroscience Institute, believes it opens the therapeutic potential of targeting the gut-brain axis to treat anxiety-related disorders by restoring the microbe composition through dietary supplementation with indoles or by introducing indole-producing gut microbes as probiotics.
 
The SK2 channels, or small conductance calcium-activated potassium channels, are a type of potassium channel that regulates neuronal excitability.
 
Wikipedia further explains that their “activation limits the firing frequency and helps regulate hyper- polarization in the neurons of the central nervous system.
 

ワオ!と言っているユーザー

Lectin: healthy protein or gut lining vandal? or both

スレッド
 
 

ワオ!と言っているユーザー

Test of Akkermansia show how it breaks down sugars for first time

スレッド
Test of Akkermansia show how...
Researchers know that Akkermansia muciniphila (AM) feeds on sugar found in the mucus digestive system. Dr. Lucy Crouch of University of Birmingham led a pig model focused on 66 enzymes that the AM microbe uses to break down mucus that is an essential part of the mucus layer lining the human gastrointestinal tract.
 
Dr. Crouch and her team found that a combination of enzymes from AM were able to completely break down the mucin, the first understanding of the molecular mechanisms behind how a microbe breaks down sugars.
 
These microbes completely break down the glycan part of mucin, a receptor for a number of pathogens. These newly characterized enzymes may be used in characterizing the different glycans that humans produce, which can be indicative of disease.
 
“AM is a hugely important microbe, and levels of the microbe can be a good indicator of overall health,” adds Dr. Crouch.
 
 

ワオ!と言っているユーザー

lithocholic acid may help extend life and support health

スレッド
lithocholic acid may help extend...
Certain gut bacteria breaks down bile acids—substances produced by the liver to digest fats. During this process, gut bacteria create a compound called lithocholic acid (LCA), according to a January 10 2025 India Times report.
 
The report references a study that shows that LCA extends life in a mice study. They found that LCA mimics the effects of fasting; helping the body repair itself and manage energy more effectively.
 
Researchers discovered that LCA activates a protein called TULP3 inside our cells, which triggers the “fasting effect” of cell repair and energy management, according to the India Times report.
 
 

ワオ!と言っているユーザー

health benefits of coffee

スレッド
health benefits of coffee

ワオ!と言っているユーザー

Gut-to-lung communication aided by gut microbe

スレッド
Gut-to-lung communication aide...
The protozoan Tritrichomonas musculis (T. Mu) is a newly discovered gut microbe that facilitates communication between the gut and lung, according to University of Toronto researchers.
This strain of gut microbe in the lung immune environment, has both beneficial and detrimental effects on our respiratory health, adds the December 19 2025 Medical Express report.
 
University of Toronto researchers found T. mu managed immune changes in the lung, which worsened airway inflammation caused by T. mu but appears to protects against respiratory infections.
 
Kyle Burrows of Simon Fraser University and molecular geneticist Dr. Jun Liu of U. Toronto working together found that T. mu-colonized in mice served as an antimicrobial shield in the airways, helping to contain tuberculosis infections, according to the Medical Express report.
 

ワオ!と言っているユーザー

Melatonin production during winter months

スレッド
Melatonin production during win...
Melatonin plays a crucial role in regulating sleep through circadian rhythm modulation in humans and animals. Beyond its association with the pineal gland, it affects multiple organ systems, such as the gut-brain axis. 
 
The November 27 2024 report in Nature, suggests melatonin may be a therapeutic agent for various dysbiosis-associated conditions due to how it affects the intestinal microbiota.
 
What happens during the dark periods of winter?
Apparently a particular strain of gut bacteria aids in the production of melatonin, especially during the winter months.
 
A few bacteria and fungi also have been shown to synthesize melatonin, first discovered in 1995 with R. rubrum, an organism estimated to be 2 to 3.5 billion years old, and Porphyrobacter (formerly Erythrobacter) longus. These bacteria produce significantly more melatonin during extended periods of darkness compared with light periods.
 
 
 
 

ワオ!と言っているユーザー

effects of synthetic dyes in foods on gut microbiota

スレッド
effects of synthetic dyes in foo...

ワオ!と言っているユーザー

Studies show increase in key gut species among coffee consumers

スレッド
Sponsored by: https://ssgusa.... Sponsored by: https://ssgusa.co/jostarribacoffee/
There are signs, among their well published health benefits, that coffee consumption can also contribute to a balanced gut microbiome. Among the trillion- plus bacteria and fungi as part of a balanced human gut, a small study found that coffee consumption can increase Bacteroides, Porphyromonas and Prevotella in our gut. This is based a study of 147 healthy individuals.
 
In a much broader study reported by Nature’s November 18 2024 issue, 22,000 shotgun metagenomic samples were studied in participants who provided detailed reports on long-term coffee consumption, showing an increase in the Lawsonibacter asaccharolyticus among participants. The aforementioned strains are considered important to maintaining a balanced and healthy gut.
 
Coffee is consumed almost worldwide and has been shown to exert beneficial effects on human health, including lowering all-cause and cardiovascular disease-specific mortality, risks of type 2 diabetes, non-alcoholic fatty liver disease and cancer, as well as other diseases (according to the Nature report).
 
 
 
 
 

ワオ!と言っているユーザー

  • ブログルメンバーの方は下記のページからログインをお願いいたします。
    ログイン
  • まだブログルのメンバーでない方は下記のページから登録をお願いいたします。
    新規ユーザー登録へ
ハッピー
悲しい
びっくり