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Researchers from Bar-Ilan University (BIU) led by Professor Omry Koren, from BIU’s Azrieli Faculty of Medicine in Israel have found that a disrupted gut microbiome due to antibiotic use in infancy can lead to aggression later on, causing changes to aggression-related genes, according to a recent September 23 2024 report in New Atlas. Said Professor Omry Koren, “disrupted microbiome during critical developmental periods can lead to persistent aggressive behaviors later in life.”

 

Aggression is a complex social behavior associated with survival modulated aggression, including by specific genes, neurotransmitters, environmental factors, and hormones especially Serotonin which is produced in our gut, according to New Atlas.

 

Chronic constipation, nausea, gastrointestinal problems, often precede a Parkinson’s diagnosis. This has been experienced by many Parkinson’s patients, according to Trisha Pasricha, MD, a gastroenterologist at Beth Israel Deaconess Medical Center and instructor of medicine at Harvard Medical School. Dr. Pasricha was interviewed in a September 8 2024 Fox Digital News article.

 

The Beth Israel Deaconess Medical Center (BIDMC) in Boston conducted a study which showing that those who sustained damage to the upper gut lining (gastrointestinal (GI) tract) are 76% more likely to develop Parkinson’s disease.

 

The soft gut lining in our digestive system can be damaged by excessive eating of foods containing lectin for example. In addition, Pasricha said taking NSAIDs like ibuprofen, drinking alcohol, stress or bacteria like H. pylori,” can be damaging to our gut lining.

 

Most gut – brain axis studies have focused on serious brain diseases such as Alzheimer’s, Parkinson’s and dementia. Very limited research has been conducted related to cognitive decline through aging. Age-related cognitive decline is inevitable for all of us.

 

Scientists decided to study the impact of gut health and aging as reported in SciTech Daily (article link below). University of North Carolina at Chapel Hill and North Carolina State University researchers examined cognitive scores of study participants and found they experienced improvement from mild cognitive impairment after receiving the probiotic Lactobacillus rhamnosus GG(LGG) for a three-month period (reported in the August 2023 issue of Science Tech Daily). Likewise, the report sighted that a decrease in abundance of Prevotella bacteria correlated with improved cognitive scores.

 

Mashael Aljumaah who is affiliated with both aforementioned universities and King Saud University in Saudi Arabia, says it “opens up new avenues for combating cognitive decline associated with aging,” as quoted in Science Daily.

 

 

 

 

EMBL researchers at the University of Split, Croatia finds our gut microbiome is implicated in the way our body responds to carcinogens and develops cancer, as quoted in July 31 2024 issue of Medical Express, and in research published in the journal Nature. Carcinogenic chemicals can cause ordinary cells to transform into cancer cells.

 

In this case, gut bacteria may contribute to the onset of cancer. The University of Split researchers discovered that only 10% of mice developed tumors who were given the cancerous chemical BBN found in tobacco that also received antibiotics.

 

On the other hand, 90% of mice given the same BBN but not the antibiotics developed cancerous tumors.

 

The full Medical Express article can be viewed here:

 

Arpana Church, a neuroscientist at UCLA’s Goodman-Luskin Microbiome Center led a study that discovered biological patterns in the microbiomes showing highly resilient people when facing stressful situations, according to a June 24 2024 NPR article reporting on the Nature Mental Health study. 

Scientists believe these pattern discoveries could lead to therapeutic treatments. Here is the full NPR article: