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Melatonin plays a crucial role in regulating sleep through circadian rhythm modulation in humans and animals. Beyond its association with the pineal gland, it affects multiple organ systems, such as the gut-brain axis. 

 

The November 27 2024 report in Nature, suggests melatonin may be a therapeutic agent for various dysbiosis-associated conditions due to how it affects the intestinal microbiota.

 

What happens during the dark periods of winter?

Apparently a particular strain of gut bacteria aids in the production of melatonin, especially during the winter months.

 

A few bacteria and fungi also have been shown to synthesize melatonin, first discovered in 1995 with R. rubrum, an organism estimated to be 2 to 3.5 billion years old, and Porphyrobacter (formerly Erythrobacter) longus. These bacteria produce significantly more melatonin during extended periods of darkness compared with light periods.

 

 

 

 

JostArriba is now 100% compostable!

Our packaging is made from plant-based materials—cassava, wood pulp, and beetroot—that protect product quality while being completely compostable.

Researchers from Bar-Ilan University (BIU) led by Professor Omry Koren, from BIU’s Azrieli Faculty of Medicine in Israel have found that a disrupted gut microbiome due to antibiotic use in infancy can lead to aggression later on, causing changes to aggression-related genes, according to a recent September 23 2024 report in New Atlas. Said Professor Omry Koren, “disrupted microbiome during critical developmental periods can lead to persistent aggressive behaviors later in life.”

 

Aggression is a complex social behavior associated with survival modulated aggression, including by specific genes, neurotransmitters, environmental factors, and hormones especially Serotonin which is produced in our gut, according to New Atlas.

 

Chronic constipation, nausea, gastrointestinal problems, often precede a Parkinson’s diagnosis. This has been experienced by many Parkinson’s patients, according to Trisha Pasricha, MD, a gastroenterologist at Beth Israel Deaconess Medical Center and instructor of medicine at Harvard Medical School. Dr. Pasricha was interviewed in a September 8 2024 Fox Digital News article.

 

The Beth Israel Deaconess Medical Center (BIDMC) in Boston conducted a study which showing that those who sustained damage to the upper gut lining (gastrointestinal (GI) tract) are 76% more likely to develop Parkinson’s disease.

 

The soft gut lining in our digestive system can be damaged by excessive eating of foods containing lectin for example. In addition, Pasricha said taking NSAIDs like ibuprofen, drinking alcohol, stress or bacteria like H. pylori,” can be damaging to our gut lining.