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“WHERE THINGS SO SMALL CAN HAVE A MASSIVE IMPACT ON YOUR HEALTH.”
Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

Four primary herbs of TCM; 伝統的な漢方薬の4つの主要なハーブ

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source: dreamstime.com source: dreamstime.com
According to a January 2021 Well and Good article by writer Kayla Hui, there are four main herbs associated for centuries with traditional Chinese medicine or TCM.

1) First is ginseng, the "granddaddy of them all". Ginseng is an adaptogen, aka a substance that helps the body react to stress and keep it in balance.

2) Though popular in Chinese culture, Huang Qi dried roots of the plant astragalus is known to protect the immune system.

3) Also well known and popularly used in Chinese and Japanese culture, the lingzhi mushroom, or ganoderma lingzhi, also known as reishi, is a polypore fungus ("bracket fungus"), that may be familiar by its fanning out shape. It has therapeutic properties that can enhance energy and increase memory.

4) The goji berry which took the health community by storm in recent years, possesses potent antioxidant and anti-inflammatory properties that help reduce stress by limiting free radicals.

https://www.wellandgood.com/chinese-herbs-longevity/amp/


伝統的な漢方薬(Traditional Chinese Medicine)の4つの主要なハーブ

筆者KaylaHuiによって書かれた2021年1月のWelland Goodの記事によると、何世紀にもわたって伝統的な漢方薬(Traditional Chinese Medicine)に関連付けられてきた4つの主要なハーブがあります。

1. 一つ目は「すべての祖父」である高麗人参です。高麗人参は、体がストレスに反応してバランスを保つのを助ける物質であるアダプトゲンです。
2. 二つ目は、中国文化で人気があるにもかかわらず、西洋ではあまり知られていない黄気は、食品添加物として理想的に使用される植物の乾燥した根を持っています。免疫系を保護することが知られているレンゲが含まれています。
3. 三つ目、中国と日本の文化でよく知られており、広く使用されているLingzhiキノコ又は霊芝は多孔質のキノコ(「ブラケットキノコ」)です。このキノコは、エネルギーを高め、記憶を増やすことができる治療特性を持っています。
4. 4つ目、近年では健康界を驚かせるゴジベリーは、フリーラジカルを制限することでストレスを軽減するのに役立つ強力な抗酸化作用と抗炎症作用を持っています。

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Fecal transplant prove effective in melanoma patients; 糞便移植は黒色腫患者に効果的であることが証明されています

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Fecal transplan...
Diwakar Dacar, oncologist at the University of Pittsburgh and colleagues evaluated the transfer of fecal matter from melanoma patients who responded well to immunotherapy compared to those patients for whom immunotherapy failed.

First reported by the Science journal February 05 2021 the results showed an increase in "CD8+ T cell activation, and decreased frequency of interleukin-8–expressing myeloid cells" which are known to suppress the immune system.

This fecal transplant treatment helped reduce size of the tumors in their patients where other treatments weren't effective. This brings up the "unproven theory", possibility that fecal transplant through microbes can potentially reach places where other treatments cannot. Again, more research is needed to confirm this.

https://science.sciencemag.org/content/371/6529/595

https://theconversation.com/amp/fecal-microbe-transplants-help-cancer-patients-respond-to-immunotherapy-and-shrink-tumors-154340


糞便移植は黒色腫患者に効果的であることが証明されています

ピッツバーグ大学の腫瘍学者であるDiwakarDacarと彼の同僚は、免疫療法が失敗した患者と比較して免疫療法によく反応した黒色腫患者からの糞便の移動を評価した。

サイエンスジャーナルによって2021年2月5日に最初に報告された結果は、免疫系を抑制することが知られている「CD8 + T細胞の活性化の増加、およびインターロイキン-8を発現する骨髄細胞の頻度の減少」を示しました。

この糞便移植治療は、他の治療法は効果的ではなかった患者の腫瘍のサイズを縮小するのに役立ちました。これは「証明されていない理論」をもたらします。微生物を介した糞便移植は、他の治療法では到達できない場所に到達する可能性があります。またまた、これを確認するにはさらに調査が必要です。

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The gut of Neanderthals

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The gut of Neanderthals
University of Bologna researchers found gut bacteria species in our gut that have been passed on from the Neanderthals. They extracted ancient DNA from 50,000-year-old faecal sediments samples of Neanderthals at the archaeological site of El Salt, near Alicante (Spain).

Researchers today know that modern influences such as processed foods, drugs, and even lifestyle has lead to a critical reduction of biodiversity in the gut microbiota.

Discovering these gut mucrobes that have existed since before humans tells us about the microbes that are essential to survival.

Bacteria often referred to as "keystone species" in both our own gut and those of Neanderthals are Blautia, Dorea, Roseburia, Ruminococcus and Faecalibacterium.

https://www.hindustantimes.com/lifestyle/health/study-reveals-nehandertals-gut-microbiota-bacteria-helping-our-health-101612589960662-amp.html

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Microbes in plants help grow healthier plant & food/ 植物中の微生物は、より健康的な植物/食品の成長を助けます

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source: dreamstime.com source: dreamstime.com
Microbes in plants known as Arbuscular Mycorrhizal Fungi (AMF) grow within the plant roots and help them grow better and be more resistant to environmental stressors, according to Dr. Nicolas Corradi, Associate Professor in the Department of Biology and Research Chair in Microbial Genomics at the University of Ottawa quoted in a February 04 2021 report by SciTech Daily.

Why is this important? It impacts the health of the plant food that we eat, making for the reason among others, why growing organically and naturally so critical to maintaining the plants nutrients. The study was able to identify how these AMF affect plant growth, and how the can be controlled by plants, leading to ways farmers can manipulate sustainable farming to improve crop yield and quality.

https://scitechdaily.com/plants-control-the-genetics-of-microbes-with-which-they-live-in-symbiosis/

植物中の微生物は、より健康的な植物/食品の成長を助けます

2021年2月4日にSciTech Dailyが報告した、オタワ大学の生物学および微生物ゲノミクスの研究委員長の准教授であるニコラス・コラディ博士によると、アーバスキュラー菌根菌(AMF)として知られる植物の微生物は、植物の根の中で成長し、彼らがより良く成長し、環境ストレスの原因に対してより耐性を持つのを助けます 。

なぜこれが重要なのか?これは私たちが食べる植物性食品の健康に影響を与え、とりわけ、植物の栄養を維持するために有機的かつ自然に成長することが非常に重要である理由になります。この研究では、AMFが植物の成長にどのように影響し、植物がどのように制御できるかを特定することができ、農家が持続可能な農業を操作して作物の収量と品質を向上させる方法につながりました。

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Gut microbiome treatment solution for every human disease?

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Scientists and the health communities of the Boston area are collaborating on microbiome research and development of treatments based on the research. That is the direction the medical community is headed, according to a January 05 2021 MIT News article.

MIT, Harvard University, The Broad Institute, and a number of Boston- based health organizations are weighing in on the gut health research and the treatments for every human disease. “In almost every disease context that’s been investigated, we’ve found different types of microbial communities, divergent between healthy and sick patients,” says MIT professor of biological engineering Eric Alm says. He and his team found contrasts between different types of microbial communities, making microbial related treatments for disease illness complicated.

What these sometimes divergent groups do agree on is that appropriate treatments are specific to each individual case. They hope their collaborations will lead to more concrete treatment solutions, such as the fecal transplants by companies like OpenBiome and personalized health recommendations by Viome.

https://news.mit.edu/2021/microbiome-research-health-0105

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The weight loss affects of teas

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The weight loss affects of teas
A recent study of volunteers by professor Professors Dr. Simeng Zhang, Kumpei Tokuyama and associates found that both the oolong tea and pure caffeine boosted fat breakdown by about 20 percent in a atudy of 12 non-obese men. The difference between the two is oolong continued to have these effects while people slept. Researchers have not yet identified the specific ingredients in oolong tea that contributes to stimulating fat oxidation, according to the article published by the National Institute of Health (1).

Dr. Tim Bond of the U.K. Tea Advisory Council is quoted in the Beet that people with obesity have low levels of a bacteria called Bacteroidetes and high levels of another bacteria called Firmictures, but tea seems to reverse this ratio back as quoted in a January 25 2021 article of The Beet (2).

“There is evidence that some of the catechins in the green tea specifically may help increase metabolism and fat burning, therefore aiding weight loss,” adds Julie Upton, M.S., R.D., co-founder of Appetite for Health in The Beet article (2).

1. https://pubmed.ncbi.nlm.nih.gov/33260552/

2. https://thebeet.com/new-study-shows-hidden-benefit-of-tea-it-helps-burn-fat-improves-gut-health/

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Naturally produced hydrogen peroxide keeps our gut healthy; 自然に生成された過酸化水素は人間の腸を健康に保ちます。

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Naturally produ...
We know not all microbes in our body are good for us. Some can be harmful. In the case of the lining of our colon an enzyme protects us by releasing hydrogen peroxide (H2O2), according to scientists at the University of California (UC) Davis Health.

A November 2020 report by Neuroscience News says this is how microbiota is kept clear of our mucous filled colon surface, thus preventing potential pathogens from forming on the lining. The discovery was made by lead author Andreas Bäumler, professor of medical microbiology and immunology at UC Davis Health.

This research points to yet another study that suggests shifting focus away from treatments by targeting bacteria to restoring the environment'so normal function.

https://neurosciencenews.com/hydrogen-peroxide-gut-microbes-17403/amp/


自然に生成された過酸化水素は人間の腸を健康に保ちます。

体のすべての微生物が私達にとって良いわけではないことを知っています。一部は有害である可能性があります 。
カリフォルニアデービスヘルス(UC Davis Health)大学の科学者によると、結腸の内壁の場合は、酵素が過酸化水素(H2O2)を放出することによって保護します。

2020年11月Neuroscience Newsのレポートによると、これは、微生物叢が粘液で満たされた結腸表面から離れた状態に保たれ、潜在的な病原体が内層に形成されるのを防ぐ方法です。この発見は、主執筆者である医療微生物学および免疫学の教授であるアンドレアス・バウムラーによって行われました。

この研究は、細菌を標的にして環境を正常な機能に戻すことにより、治療から焦点を移すことを示唆するさらに別の研究を示しています。
この研究は、細菌を標的とする治療から環境を正常な機能に戻すことに焦点を移すことを示唆するさらに別の研究を示しています。

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Treatment of diabetes tied to specific gut bacteria strains; 糖尿病治療は腸内細菌の特定な菌株に関連しています

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Out of the trillions of bacteria residing in our gut, scientists now know there are specific strains that positively affect treating type 2 diabetes, leading to the possibility of probiotic treatment for the disease.

Research led by Natalia Shulzhenko, an associate professor of biomedical sciences at Oregon State University and co-author Andrey Morgun found that bacteria influencing our personal health are not only those that have been identified as "keystone species", according to a January 07 2021 report by Medical News Today, and therefore, is often unique to the individual.

Scientists found down the list to four bacteria that appeared to play a key role in reducing or intensifying the harmful effects of a Western diet: Lactobacillus johnsonii, Lactobacillus gasseri, Romboutsia ilealis, and Ruminococcus gnavus. They found how gut bacteria influences the way a person metabolizes glucose and lipids. For example, L. johnsonii and L.gasseri showed to improve glucose tolerance.

These findings might help develop treatments for type 2 diabetes, say the authors.

https://www.medicalnewstoday.com/amp/articles/meet-the-bacteria-that-might-help-treat-diabet
es

https://www.news18.com/amp/news/buzz/beneficial-gut-bacteria-can-play-key-role-in-treating-diabetes-3247631.html

糖尿病治療は腸内細菌の特定な菌株に関連しています

現在、科学者たちは、腸内に存在する何兆ものバクテリアの中から、2型糖尿病の治療や保護に積極的に影響を与える特定の菌株があることを知っています。

2021年1月7日のメディカルニュースのレポートによると、オレゴン州立大学の生物医科学の准教授であるNataliaShulzhenkoと共著者のAndreyMorgunが率いる研究では、私たちの健康に影響を与える細菌は「キーストーン種」として特定された細菌だけではないことが見付けました。そのため、多くの場合、個々に固有のものです。

科学者は、西洋型食生活の有害な影響を軽減または強化する上で重要な役割を果たしていると思われるLactobacillus johnsonii, Lactobacillus gasseri, Romboutsia ilealis, and Ruminococcus gnavus 、4つの細菌にリストを絞り込みました。
彼らは、これらの腸内細菌がどのように人々がブドウ糖と脂質を代謝する方法に影響するかを発見しました。たとえば、L。johnsoniiとL.gasseriは耐糖能を改善することを示しました。
著者が、この発見は、将来的に、2型糖尿病のためのプロバイオティクス治療法の開発に役に立つと言います.

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More links to food and our gut health

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Source: dreamstime.com Source: dreamstime.com
According to a January 15 2021 report by Medical News Today, researchers identified 15 gut microbes associated with lower risks and 15 with higher risks for common illnesses, like diabetes and heart disease.

The study identified links between certain food products and gut bacteria and biomarkers of obesity, cardiovascular disease, and impaired glucose metabolism, which are all recognized risk factors for severe COVID-19, says the article.

A recent January 11 2021 New York Times article quoted Dr. Sarah E. Berry, a nutrition scientist at King’s College London whose research studied the diet of over a thousand individuals. The study found that diet full of highly processed foods with added sugars, salt and other additives had serious negative health effects.

Researchers agree that no "one diet fits all". The Times article quotes Dr. Andrew T. Chan, a co-author of the study and a professor of medicine at Harvard Medical School and Massachusetts General Hospital: “There is a lot of variation,” pointing out that the same diet can have completely different outcomes between individuals.

Examples of “good” strains identified by the study include Prevotella copri and Blastocystis, both of which reduce the risk of heart disease.

https://www.medicalnewstoday.com/amp/articles/intimate-links-between-diet-gut-microbes-and-illnesses-identified

https://www.nytimes.com/2021/01/11/well/eat/diet-gut-microbiome.html

https://www.wcvb.com/amp/article/new-clues-into-gut-microbiomes-effect-on-health/35228010

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Can fluoride stem growing concern of antibiotics in our synthetic biology world?

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Can fluoride stem growing con...
The dangers around overusing antibiotics is not new to the scientific community, as the number of antibiotic-resistant microbes increase. These unwanted microbes are developing resistence to the antibiotics, diminishing their therapeutic efficacy. Researchers are concerned not only about its negative influence on our body such as our gut microbiome, but also the impact these synthetically engineered microbes have when released into the environment.

In a January 04 2021 article in Science Daily, UC Santa Barbara chemical engineer Michelle O'Malley points out that "with the advent of synthetic biology, there is increasingly a risk that things we're engineering in the lab could escape and proliferate into ecosystems where they don't belong."

A process developed by Justin Yoo, a former graduate student researcher in O'Malley's lab, found that fluoride can eliminate this problem. Microbes that escape into the natural environment would die as soon as it encounters fluoride, thus preventing propagation, according to the Science Daily article.

https://www.sciencedaily.com/releases/2021/01/210104141521.htm

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