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“WHERE THINGS SO SMALL CAN HAVE A MASSIVE IMPACT ON YOUR HEALTH.”
Herbsprout is a webblog and podcast dedicated to sharing the health benefits of herbs, food, innovations related to our gut microbiome. Herbsprout seeks to bridge the vast chasm dividing the mainstream medical community and alternative medicine.

More gut health links to Autism

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More gut health links to Autism
A March 11 2020 report by The Conversation, a collaboration between three Australian universities, conducted two studies, one of mice and the other of human twins with autism, showing a gene mutation called neuroligin-3. It is known among professionals in the field that people with autism are more likely to experience gastrointestinal disorders than the general population. The twins were diagnosed with esophagitis and diarrhea, and the gene- mutated mice also showed gut microbiome deficiencies associated with diabetes and inflammatory bowel disease. Other reports found that children with autism (ASD) were four times more likely to have gastrointestinal issues than children without autism ( see https://theconversation.com/amp/science-continues-to-suggest-a-link-between-autism-and-the-gut-heres-why-thats-important-118914 ). The three collaborating universities of The Conversation are RMIT, La Trobe, and Monash Universities.

Parents of children have long claimed that giving their autistic children a healthy probiotic diet has helped reduce their autistic behaviors. Studies show that children with ASD often have a mix of gut microbes that substantially differ from children without ASD. A January 22, 2020 article in Nature references a University of Arizona study on microbiota transfer therapy, which would be used to recolonize the guts with bacteria of children suffering from autism. The study found other research showing the following deficiencies of gut microbiomes in autistic people: Bifidobacterium, Blautia (needed to produce bile acids to produce serotonin), Veillonellaceae, Coprococcus and Prevotella. Conversely, researchers found an excess of the Clostridia bacterial pathogens (know to disrupt production of serotonin in the gut) (see https://www.nature.com/articles/d41586-020-00198-y ).

April is Autism Awareness month. Global Engage a world leading çonference organisers published a variation of this blog on their website at http://www.global-engage.com/life-science/gut-brain-axis-insights-why-the-microbiota-holds-therapeutic-potential-for-neuro-developmental-disorders/ .
#ASD #autism #gutbacteria #gutbrainaxis #guthealth #microbiome #serotonin

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Consensus on Indian Marma/ Chinese, acupressure/ acupuncture as a remedy

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source: shutterstock.com source: shutterstock.com
Acupressure and acupuncture target "vital energy points" in our bodies, according to traditional Indian medicine, Ayurveda. The term marma and acupressure points are similar to each other in this way. There are certain critical points in our bodies that must be considered in surgery for example, according to Ayurvedic tradition, that should be avoided.

A book by Franc Ros, called The Lost Secrets of Ayurvedic Acupressure, goes into detail about the similarities and differences between marma and Ayurvedic medicine's acupressure (see book, Lost Secrets of Ayurvedic Acupuncture https://www.amazon.com/dp/0914955128/ref=cm_sw_r_taa_BacyEb04FCA1A ).

A common question is, are acupressure and acupuncture effective at helping to relieve physical pain? Human trials consistently suggest they do, but it's hard to factor in the placebo effect. There is little evidence that suggests it addresses other health conditions.

Acupuncturists and acupressure use the same points for their respective practices. Acupuncturists believe it corrects energy imbalances in the body. Western doctors believe it stimulates natural chemicals in your body called endorphins that block pain signals, according to WebMD.

The National Institute of Health says that complications from acupuncture treatment is rare, and is relatively safe. Both accupressure and acupuncture have become more common treatments for pain conditions, such as:

● Low-Back Pain,
● Neck Pain,
● Osteoarthritis/Knee Pain,
● Headache, among others

(see NIH page, https://nccih.nih.gov/health/acupuncture/introduction ).

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Studies show how serotonin, our gut microbiome impacts our "second brain"

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Studies show how serotonin, o...
A February 07, 2020 article by Psychiatry Advisor examines the close connection between our mood, depression and our gut microbiome. Often called our "second brain", the enteric nervous system (ENS) is two thin layers of more than 100 million nerve cells lining your gastrointestinal tract from esophagus to rectum. The primary role of ENS? It regulates our digestive system - the release of enzymes and ingestion of nutrients that we need. The study of our three gut-brain axis - the nervous system, ENS, and our digestive system - are coming closer and closer to offering long term health solutions for not only depression but for other brain diseases. Scientists found that the hypothalamic–pituitary–adrenal (HPA) axis, by activating cytokines, trigger the release of cortisol, a potent stress hormone. It is bi-directional. When it becomes unstable our body becomes stressed which can lead to depression (see articles https://www.hopkinsmedicine.org/health/wellness-and-prevention/the-brain-gut-connection and https://www.psychiatryadvisor.com/home/depression-advisor/a-closer-look-at-the-importance-of-gut-mechanisms-in-depression/).

Senior author Elaine Hsiao says researchers hope to build on their current studies at UCLA to learn whether microbial interactions with antidepressants have consequences for health and disease, according to the September 2019 report (Credit: by Stuart Wolpert, University of California, Los Angeles; Reed Hutchinson/UCLA).

A study in mice led by UCLA biologists strongly suggests that serotonin and drugs that target serotonin, anti-depressants such as Prozac can have a major effect on the gut's microbiota—the 100 trillion or so bacteria and other microbes that live in the human body's intestines. Hsiao's team of researchers found that Turicibacter sanguinis, a common gut microbe, can signal nearby intestinal cells to release serotonin. Serotonin—a neurotransmitter, or chemical messenger that sends messages among cells—is known as the "happy chemical as it positively influences our mood. An estimated 90 percent of the body's serotonin is produced in the gut.

"Previous studies from our lab and others showed that specific bacteria promote serotonin levels in the gut," lead author Thomas Fung said. "Our new study tells us that certain gut bacteria can respond to serotonin and drugs that influence serotonin, like anti-depressants. This is a unique form of communication between bacteria and our own cells through molecules traditionally recognized as neurotransmitters." (See articles, American Chemical Society and Phys.Org - https://cen.acs.org/biological-chemistry/microbiome/Serotonin-helps-gut-microbes-thrive/97/i35 and
https://phys.org/news/2019-09-serotonin-popular-anti-depressant-affect-gut.html ).

The same month of September (September 17) of 2019, Professor Damien Keating, Head of Molecular and Cellular Physiology at Flinders University found that our gut microbiome signals cells to serotonin production in the gut, which Dr. Keating "showed to be increased in obese humans, and this rise in blood serotonin causes significant metabolic problems.” These insights, he suggests, provides valuable first- step data points that can lead to visibility into the role of our gut microbiome, serotonin, and blood sugar levels which can aid in addressing obesity and diabetes (See Neuroscience News article, https://neurosciencenews.com/gut-bacteria-serotonin-blood-sugar-14930/ ).

Another study in Nature recommends fasting as a way to "reboot the system". According to a February 18, 2020 Nature article, "Intermittent fasting (IF) regimens which involves dietary restriction, have shown to increase lifespan, promote energy metabolism, and reduce the risk of developing various age-related pathologie." It is believed that IF influences our gut microbiome to create these results. Theoretically it can play a role in our mood and stress as the previously mentioned articles suggest (see article, https://www.nature.com/articles/s41467-020-14676-4?utm_ ). Special thanks to Yeirim Kim, Herbsprout Facebook member for sharing this post.

A more natural alternative to antidepressants, a previous Herbsprout blog references herbs that support the production of serotonin. For example, Herbs that help boost serotonin levels include oatstraw, and the roots of angelica, burdock, dandelion, ginseng, wild yam and black cohosh.
https://en.bloguru.com/healthtech/356055/herbs-that-support-the-happy-chemical

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Hinoki oil tests positive for easing stress

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Hinoki, Japanese Cypress. Hinoki, Japanese Cypress.
Heard about Hinoki oil? It comes from a tree by the same name, the Hinoki Japanese cypress. A lemony, balsamic-scented oil, Hinoki is both soothing and relaxing, two components that favor the oil for baths and for massage or just to help you sleep. Try diffusing it or put a drop on your wrists and inhale.

Hinoki oil contains phytoncides, which are volatile substances that plants emit to protect against pathogens and insects. They possess insecticidal, antimicrobial, and antifungal properties. It also contains alpha-pinenes or α-Pinene, which is an organic compound of the terpene class. It is an alkene that is found in the oils of many species of coniferous trees, such as pine and hinoki. It is also found in the essential oil of rosemary (Rosmarinus officinalis) and Satureja myrtifolia (also known as Zoufa in some regions). This chemical is known to be anti-inflammatory, possibly antimicrobial, and a memory aid as an acetylcholinesterase inhibitor.

Distilled from wood discards of the timber industry, the Hinoki essential oil is offering a sustainable solution to forest management. In Japan, the wood of the Hinoki is highly prized but the forests are over populating in some areas. Through it’s its sourcing program for the Hinoki essential oil, doTERRA International, the essential oils company, is encouraging the creation of jobs in rural Japan while helping to clear the forests of wood by-products. .

In Japan, Hinoki is a treasured wood used in the building of some of the oldest, existing buildings, and valued for its light scent for incense. It is commonly used to:

● Heals wounds. Hinoki essential oil has antiseptic qualities which helps to heal minor cuts, scrapes and wounds. ..
● Relieves muscle spasms. ...
● Eliminates respiratory conditions. ...
● Relieves anxiety. ...

Hinoki oil is available as a limited offer, and you can get a free 5 mL bottle of Hinoki oil as the Doterra POM (product of the month) for 125PV LRP orders placed. See https://www.doterra.com/US/en/hinoki-oil .

Co-authored by Cindy Postma. You can become a doterra member here and receive discounts on natural essential oils: https://www.doterra.com/US/en/site/cindypostma .

More information about the influence of our gut bacteria and stress, https://en.bloguru.com/healthtech/355962/stress-and-the-gutbrain-connection
#bacteria #chinesemedicine #diet #easternmedicine #essentialoilso #gutmicrobiome #health #healthinnovation #herbalmedicine #herbs #japanesemedicine #mindbody #naturopathichealth #plantnutrition #spices

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Ulcerative colitis linked to missing gut microbe; 70% of our body's molecules produced by gut bacteria

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Ulcerative colitis linked to miss...
#crohnsdisease #gutbacteria #guthealth #microbiome #ulcerativecolitis

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Mediterranean diet & herbs show improved gut microbiome diversity

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Source: getty images Source: getty images
Seniors can be a good case study for diet efficacy. A February 17, 2020 Medical Express and British Medical Journal reported an analysis of the gut microbiome of 612 people aged 65 to 79. It is commonly understood that as we age our gut microbiome diversity progressively decreases, particularly if we consume a limited diet in our waning years. People were tested in this age group before and after 12 months of either eating their usual diet (n = 289) or a Mediterranean diet (n = 323), rich in fruits, vegetables, nuts, legumes, olive oil and fish and low in red meat and saturated fats, and specially tailored to older people (NU-AGE diet).

The participants, who were either frail (n=28), on the verge of frailty (n=151), or not frail (n=433) at the beginning of the study, lived in five different countries: France, Italy, Netherlands, Poland, and the UK. 323 individuals agreed to follow a Mediterranean-type diet for 1 year, while the rest continued with their usual diets and acted as a control group.

Sticking to the Mediterranean diet for 12 months was associated with beneficial changes to the gut microbiome, rich in microbiome diversity.

(See articles, https://medicalxpress.com/news/2020-02-mediterranean-diet-gut-bacteria-linked.amp ; and
https://www.medicalnewstoday.com/amp/articles/mediterranean-diet-linked-to-gut-microbiome-improvements

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Profile: Viome’s Genetic Code Principles

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Links between gut health and mania/ bi-polar disorder

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Links between gut health and ...
A September 04, 2019 article in the New Scientist suggests that eating a proper amount of psychobiotics, a derivation of probiotics, can improve one's mental health. (see
https://www.newscientist.com/article/mg24332460-500-how-what-you-eat-directly-influences-your-mental-health/ ). Probiotics may help improve a variety of mental health conditions, in part due to an anti-inflammatory effect, including those suffering from manic depression and bi-polar (BP) disorders. Psychobiotics are believed to mitigate chemical imbalance in the brain, and offer an alternative to drug treatment, claims the article.

Lithium has become the most accepted remedy used for treating BP. Studies such as the 2020 Neuropsychobiology report have found little connection between lithium intake and Escherichia coli or Lactobacillus rhamnosus, except that it appears to support a stronger richness and diversity of these species. However, they found a noticeable increase in Clostridium, Peptoclostridium, Intestinibacter, and Christenellaceae following lithium treatment (see https://www.karger.com/Article/FullText/504496 ). These results suggest a connection between our gut microbiota and BP treatment using lithium.

SAMPLE HUMAN TRIALS:

Researchers from Johns Hopkins University School of Medicine did a study to determine if probiotics could help recently discharged manic patients, according to a Harvard Health Publishing blog of June 25, 2018. Two groups of 33 patients were given Lactobacillus and Bifidobacterium species to one group and a placebo to the second group over a 24 week period.

The results for the rates of rehospitalization were 51.1% in the placebo group and 24.2% in the group who took probiotics. On average, the reduction in readmission was 74% lower in the probiotic group, and a 90% reduction of hospitalization in the group with the highest inflammation score. Additionally, patients who took probiotics and were rehospitalized stayed in the hospital on average 2.8 days, compared with 8.3 days for those taking placebo.

A Nature article in February 2019 referenced human trials that found connections between coprococcus and dialister bacteria, with lower levels contributing to mental health issues and specifically depression (see article, https://www.nature.com/articles/s41564-018-0337-x ).

While tests on mice are less reliable than human trials, they can effectively make connections between similar human functions. For example, The Scientist article reported that study coauthor Julio Licinio, a psychiatrist at SUNY Upstate Medical University in Syracuse made fecal transplants of schizophrenic mice that verified lower glutamate, glutamine, and GABA in their hippocampi. These are key amino acid neurotransmitters that are essential for brain function (see https://www.the-scientist.com/news-opinion/gut-microbes-may-play-a-role-in-mental-health-disorders-66039/amp ).

What scientists can say with some accuracy is that there is a link between our gut bacteria and mental health. One step further, they've identified specific species of bacteria, keystone species such as bifidobacteria and lesser known species such as coprococcus and dialister bacteria. The next steps will be to prove efficacy and FDA approval as a form of treatment in mental health patients. When this might be achieved is still to be determined, but scientists are getting closer.
#ai #bacteria #datascience #diet #gutmicrobiome #health #healthinnovation #healthtech #herbalmedicine #herbs #mentalhealth #plantnutrition #probiotics #psychobiotics #spices

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"I am who I am" because of my gut bugs?

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"I am who I am" because of ...
A February 13, 2020 article published by Psychology Central claims that our personality is shaped by the bugs, or microbes, in our gut.

Microbial diversity seems to be the key indicator to a healthy personality. Strong microbial diversity supports good mental health while a low microbial diversity points toward mental health problems such as autism or neuroticism. "Personality is both inherited and influenced by one’s environment. And the environment inside humans may matter just as much as the external environment", says Katerina Johnson in the Inverse article, and a research associate at Oxford. It is believed based on ongoing research that a lack of the Akkermansia, Lactococcus, and Osciollospir bacteria in our gut shows a tendency to autism, says the report (source: https://www.inverse.com/mind-body/microbiome-mental-health-study-links-gut-bacteria-personality/amp ). Conversely, a study of primates shows that social interactions can promote gut microbiome diversity, adds Dr. Johnson (see https://psychcentral.com/news/2020/02/13/gut-bacteria-may-be-linked-to-personality-traits/154172.html ). So the research suggests it goes both ways, even though it is not explicitly stated in these articles. We are predisposed in part to being social or anti-social based on the pre-existing level of microbiome diversity in our gut, but we can promote healthy microbiome diversity in our gut by being more social.

BBC Science reported in December 2019 that probiotics and prebiotics by nurturing and nourishing our gut bugs can help ease stress and anxiety, even aid in reducing other mental health risks. (See article, https://www.sciencefocus.com/the-human-body/psychobiotics-your-microbiome-has-the-potential-to-improve-your-mental-health-not-just-your-gut-heath/amp/ ). So yes, be at ease; the bottom line is we do have self determination; we can steer and shape and mold our own personality. . . with a little help from our microbiome friends.
#autism #braingutaxis #gutbacteria #guthealth #mentalhealth #microbiome

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Our microbiota changes over time as we age

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According to the PLOS Pathogens Journal July 25, 2019 article "Microbiome evolution during host aging ", our gut microbiota "undergoes dynamic changes through time as it integrates and responds to signals from the environment," and our genetics has very little to do with these changes. However, what we eat, what types of drugs we consume, even our social and physical environment have a significant impact on the microbial content of our gut.

These microbiota remain dynamic throughout our lives, continually changing as we grow older. It is possible, according to the report, that as we age, the changes in our gut microbiome may contribute to our aging and increased vulnerability to disease and frailty, thought our understanding of these changes are still not well understood. Just like our bodies age, so do our gut microbiome, and they weaken over time and incur damage. Our younger bacteria support a stronger immune defense, while the efficacy of aging bacteria is compromised. Younger bacterial strains carry adaptive variants and mutations, enabling it to adapt to changing environments.

More details around studies backing these assertions are available here, https://doi.org/10.1371/journal.ppat.1007727 .

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