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Chinese herbal impacts on gut health

9月

18日

Radix Scutellariae also known as baical skullcap seed/ root is the root of Scutellaria baicalensis, the source of the 2,000 year old Chinese medicine Huang Qin.

In addition to animal studies, several studies of natural products have been performed on human gut microbiota. Gegen Qinlian Decoction (GQD), a traditional Chinese herbal formula, reshaped the gut microbiota in a clinical study by China Pharmaceutical University (see reference below) in which 187 T2D (type 2 diabetes) patients participated. The data showed that the symptoms of T2D, such as fasting blood glucose levels and hemoglobin A1c (HbA1c) levels, were ameliorated in GQD-treated patients, with increased amounts of beneficial bacteria, including Faecalibacterium, Gemmiger, Bifidobacterium, and Escherichia. Radix Scutellariae (baical skullcap seed/ root) in GQT is the main herbal component that facilitated the potent inhibition of MMP-2. MMP-2 (matrix metalloproteinase-2) contributes to cancer cells migration and the progression of breast cancer, among others. GQT is also widely used to treat diarrhea and inflammation symptoms in various gastrointestinal disorders. (see https://www.sciencedirect.com/science/article/pii/S0753332218369075).

Another clinical study involving ten obese Korean women was conducted to investigate the antiobesity activity of the water extract of Ephedra sinica Stapf. This study revealed that, in seven of the ten obese women, BW and body mass index (BMI) were decreased after administration of this herb. (source: State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Basic Medicine, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China. Contact Qinglong Guo; qinglongguo@hotmail.com and Na Lu; nalu@cpu.edu.cn). ).

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What about ginseng root and gut health?

9月

10日

We know that ginseng is healthy for the body. But how does ginseng promote health? and is it beneficial for the long term? The short answer is yes, it is generally beneficial to our microbiome health for the long term.

A report in the July 2018 Journal of Ginseng Research (Volume 42, Issue 3; see https://doi.org/10.1016/j.jgr.2017.04.011) and a separate June 2018 study by Ministry of Education Key Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine (Shanghai Jiao Tong University, Shanghai, P.R.C.; see article, https://www.ncbi.nlm.nih.gov/pubmed/29896600), investigated the effect of Ginseng extracts on the structure of gut microbiota.

This report found positive affects of the "host-gut metabolism, immune system, the anti-inflammation process and the gut intestinal microbiota structure" when consuming ginseng extract over the long term. The research was based on the application of a 16S rRNA microbial sequencing technology. For example, the increased abundance in tested host groups of Bifidobacterium and Lactobacillus, interleukin 4 (IL4), and IL10 and immunoglobulin A (IgA) levels demonstrated that Ginseng extracts contribute to enhancements of probiotics. Results may vary from person to person.

A 2015 Journal of Ethnopharmacology reported that out of the 7 Chinese traditional herbs, red ginseng is the most effective in promoting the growth of probiotics including Lactobacillus and Bifidobacterium.

In a 2019 study by the Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, the antiobesity effect of ginseng varied when the composition of gut microbiota was altered. The abundance of Subdoligranulum, Oscillibacter, and Akkermansia in the gut associated with changes in BW and BMI, whereas Lactobacillus was linked to body fat percentage

#ai #artificialintelligence #bacteria #datascience #diet #gutmicrobiome #health #healthinnovation #healthtech #herbalmedicine #herbs #machinelearning #mindbody #plantnutrition #spices

Brain Health Benefits of Sage

9月

1日

Sage possesses a number of properties that support brain health. Camphor, carnosic acid, carnosol, and phenolic acids are among the known anti-oxidant and healthy components of sage.

▪ Camphor is an oily substance known to stimulate nerve endings. It gives sage its pungent smell.

▪ Carnosic acid and carnosol trigger a molecule known as peroxisome proliferator-activated receptor gamma (PPAR-gamma) that helps regulate blood sugar, lipids, and inflammation.

▪ Phenolic acids are believe to protect cells from the oxidative damage caused by free radicals in the brain.

See "Health Benefits of Sage", https://www.verywellfit.com/add-flavor-and-lower-cholesterol-with-sage-4069887.

#Ayurvedicmedicine #Japanesehealth #ai #artificialintelligence #bacteria #datascience #diet #dosha #gutmicrobiome #health #healthinnovation #healthtech #herbalmedicine #herbs #machinelearning #mindbody #plantnutrition #spices

Turmeric - The Power Herb

9月

1日

Curcumin a powerful anti-inflamatory herb/ spice, is a key compound found in turmeric root. Scientists now believe that chronic, low-level inflammation plays a major role in almost every chronic, Western disease. This includes diseases of the heart and brain, such as Alzheimer's.

Neurons are capable of forming new connections, but in certain areas of the brain they can also multiply and increase in number.

One of the main drivers of the process where neurons form new connections and actually multiply in numbers, is the brain-derived neurotrophic factor (BDNF) hormone. Curcumin is able to boost brain levels of BDNF. BDNF is a type of growth hormone that can also delay the progression of Alzheimer's and is believed to improve memory.

Turmeric is a particularly strong "anti-oxidant" that protects your body from free radicals, which are damaging to our body.

Curcumin blocks NF-kB, a molecule that travels into the nuclei of your cells and turns on genes related to inflammation. NF-kB is believed to play a major role in many chronic diseases, according to Healthline; see https://www.healthline.com/nutrition/top-10-evidence-based-health-benefits-of-turmeric#section2.

Curcumin may help prevent heart disease. It improves the function of the endothelium, which is the lining of your blood vessels. Endothelium dysfunction is a major driver of heart disease. It also reduces inflammation and oxidation. Now that's a power herb, arguably the most powerful herb.

Curcumin could improve pancreatic cells and decrease glucose levels, as well as other metabolic profile in T2D (type 2 diabetes) or atherosclerosis through inhibition of iNOS and COX-2. Furthermore, a curcumin-supplemented diet increased the richness of lactobacillales and improved the index of colon tumors. Ginsenoside also protected cardiac function and decreased blood glucose levels. (See
https://www.hindawi.com/journals/ecam/2019/2682748/
Contact Qinglong Guo; qinglongguo@hotmail.com and Na Lu; nalu@cpu.edu.cn).

#ai #artificialintelligence #bacteria #datascience #diet #gutmicrobiome #health #healthinnovation #healthtech #herbs #machinelearning #mindbody #plantnutrition #spices

Anti-microbial herbal treatments

8月

30日

While other blog entries are focused on the healthy balance of trillions of microbes that reside inside our bodies, this entry discusses the unhealthy invasive microbes that are external to our bodies. “Health care was originally designed to address infectious diseases” (invasive microbes), and treating diseases were focused on “anti-microbial” treatments and today, anti-biotic treatments. This approach has its merits. However, anti-biotics are known to suppress the healthy growth of gut microbiome.

The preferred alternative for disease prevention might be the use of herbs in a person’s diet; a naturopathic “anti-microbial” approach instead of anti-biotic treatments. This is not to discourage the use of anti-biotics in emergency or critical care situations. However, the ongoing preventive consumption of “natural antibiotics” are less disruptive to the system. Again, these are “external” disease- prone microbes that can disrupt our body’s health.

Anti-microbial Herbs:

There are a number of anti-microbial herbs which serve to protect humans against invasive bacteria or viruses. These include oregano oil, manuka honey, garlic, onions, and echinacea, to name a few.

• Oregano oil is one of the most powerful antibacterial essential oils because it contains carvacrol and thymol, two antibacterial and antifungal compounds. In fact, research shows oregano oil is effective against many clinical strains of bacteria, including Escherichia coli (E. coli) and Pseudomonas aeruginosa.

• Manuka honey can effectively inhibit multiple drug-resistant pathogens, indicating it has a broad spectrum of antibacterial capabilities unlike most antimicrobial agents.

• Garlic, especially raw garlic, contains chemical compounds, including allicin, have been proven to display antimicrobial activity and work to kill pathogens that are responsible for both common and rare infections. Garlic has been used for centuries to combat infectious diseases.

• Onions is a food often used in mixed vegetable dishes, soups, and stir fry meals. Onions contain powerful flavonoids that have antibiotic effects, and, like garlic, they contain therapeutic sulfur compounds called cysteine sulphoxides.

• Echinacea is a powerful immune system stimulator that can fight a number of infections.

#antimicrobiome #bacteria #datascience #diet #health #healthinnovation #healthtech #herbalmedicine #herbs #naturopathicmedicine #plantnutrition #spices

自己紹介

By HerbSprout.com

https://herbsprout.home.blog/ HERBSPROUT ADVISORY BOARD: ___________________________

●Jenny Pandol, Co-owner/founder/ COO, Microbiome Learning Center;
●Dr. Sabine Hazan, Founder and CEO, Progenabiome and Ventura Clinical Trials;
●Naveen Jain, Founder & CEO, Viome
●Hans Parge, ex-Pfizer director;
●Rob Greenlee, VP, Libsyn;
___________________________

●Cindy Postma, essential oils;
●Chris Kenji Beer, herbs & microbiome;
●Ely Diana, translation/ support services.
___________________________

Cindy Postma has been a writer and editor across all disciplines. She has been an instructor of Asian studies at Kings College (Cambridge), Columbia, and Cornell. She received her PhD from Kyoto University, Masters from Columbia University, and undergraduate from The University of Washington. She is proficient in four Asian languages and French. ____________________________

I am Chris Kenji Beer, Herbsprout writer and editor. I come from a family of health nuts. My mom was a psyche major and shared her Japanese culinary tradition. Uncle Tetsuo was and cousin Satoru Harada is a surgeon. Aunt Shigeko was a dietitian in Hiroshima before complications from the nuclear fallout took her life. I am currently enrolled at Bastyr University's Ayurvedic Health Advisor program. In the past, I spent many years researching health care. I was published on the topic "Japanese Health Care for the Elderly" by the U.S. - Japan Foundation, and as co-author of health care reports for National Conference of State Legislatures Health Services Program, NW Asian Weekly, & as Editor/ co-Publisher of Asia Pacific Economic Review. Email us with questions or comments @ sales@mzinger.com. ____________________________

The contents of this webblog is not intended to be used to treat, cure, mitigate, or diagnose any medical condition. The readers must consult your doctor before you make any changes that could affect your health.

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