How Gut Microbiota Contributes to Depression
12月
21日
Experimental evidence links changes in the chemokine network to depressive behavior, and researchers of clinical studies indicated an association between neuroinflammation and MDD, according to the report. This and other similar results of studies have generated increased interest in the use of anti-inflammatory microbiome agents in the treatment of MDD. Another article by Nature Microbiology found two types of bacteria, Coprococcus and Dialister, which are depleted in people with depression. Researchers reported this in a February 4, 2019 in Nature Microbiology article.
Other studies suggest that certain probiotics can serve as effective antidepressants. 34 controlled clinical trials, led by researchers from the Department of Psychiatry and Human Behavior at the Warren Alpert Medical School at Brown University (Rhode Island, USA) came to this conclusion. Of the 34 clinical trials, 27 interventions were probiotic and 7 were prebiotic, including Bifidobacterium longum, Bacillus coagulans, and Lactobacillus alone or in combination with Bifidobacterium. Each demonstrated anti-anxiety and/or anti-depressant effects. See the following article published June 04, 2019 at https://www.gutmicrobiotaforhealth.com/en/a-new-meta-analysis-of-controlled-clinical-trials-shows-the-antidepressant-and-anxiolytic-potential-of-probiotics/ .
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