Microbial treatments for Parkinson's still premature
11月
17日
While several findings were replicated in various studies, such as an increase of Verrucomicrobiaceae and Akkermansia and a decrease of Prevotellaceae, the investigators also found numerous differences.
There is no standard procedure established for clinical research on the subject, making the results difficult to collectively evaluate. "Procedures for collection, storage and shipment of the stool samples varied considerably; almost all studies used different DNA extraction kits; different DNA sequencing protocols were used; and different bioinformatics and statistical methods can further lead to different results." In addition, the study populations differed considerably between studies in terms of age, percentage of females and Parkinson’s disease characteristics, such as disease duration and the clinical subtype.
"It is important to emphasize that no microbiota-based treatment for PD exists to date," says Dr. Scherperjans. "We advise PD patients not to start self-treatment with probiotics or undergo fecal microbiota transplantation without consulting with their doctors in order to avoid potential harm.”
However, research has determined a connection between gut microbiome and PS progression, though further studies are needed to identify how they are connected. This blog is a continuation of the earlier herbsprout.com blog entry, "Parkinson's may originate in the gut": http://herbsprout.com/357162/parkinsons-may-originate-in-the-gut
https://neurosciencenews.com/parkinsons-microbiota-15191/amp/
神谷保険