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Nacalai USA's Blog

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*** 20% OFF *** Exclusive Online Discount on SunShell, SunArmor, and More

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SunShell, SunArmor, Sunniest, ... SunShell, SunArmor, Sunniest, Sunrise HPLC columns : 20% OFF
We are running a special promotion of SunShell, SunArmor, Sunniest and Sunrise columns. For a limited period of time, all columns can be purchased at a 20% off the list price using the promo code SUN20.

SunShell HPLC columns
SunShell SFC columns
SunArmor HPLC columns
Sunniest HPLC columns
Sunrise HPLC columns

The discount will be:
- applied only to the columns listed on our website.
- not available to overseas.
- cannot be combined with any other offer, promotion or discount.

*** PromoCode: SUN20 ***
*** Valid until 04/30/2023 ***
#coreshell #drug #hplc #ms #specialoffer #sunarmor #sunshell

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New Product: Centrifugal filtration plate for 96-well & 384-well

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Centrifugal filtration plate, 96-w... Centrifugal filtration plate, 96-well type
For users of flow cytometers, this is a mesh-equipped microplate into which specimens can be dispensed using a multichannel pipette, an automatic dispenser, or other tools. The microplate can be stacked on top of another one, and then the specimens can be filtered at once by centrifugation. This is a convenient solution for those who want to operate more easily and save time.


For more detail, please click below.
Centrifugal Filtration Plates for 96-well and 384-well
#assay #cellculture #drugdiscovery #facs #filtration #flowcytometer #media #newproduct #plateseal #strainer

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30% OFF Precast Gel

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30% OFF Precast Gel
30%-off CosmoPAGE Precast Gel.

*End Date: 4/30/2023

Please click the link below for more information:

CosmoPAGE Precast Gel
#specialoffer

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ON SALE until Mar 31

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ON SALE until Mar 31

20%-off  Protease Inhibitor Cocktail Tablets, EDTA-Free (Cat#: NU01069, 20 tablets) and RIPA Buffer (10X) (Cat#: 08714-04, 1 set).
Please use the promo code "PICT20" for your purchase.

*End Date: 3/31/2023

Please click the link below for more information:

Protease Inhibitor Cocktail Tablets, EDTA-Free

RIPA Buffer
#newproduct #specialoffer

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Separation of highly hydrophilic nicotinamide metabolites using a COSMOSIL PBr column

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Separation of highly hydrophili...
We published "Separation of highly hydrophilic nicotinamide metabolites using a COSMOSIL PBr column" in MethodsX, 2023, 10. 102061.

DOI: https://doi.org/10.1016/j.mex.2023.102061

Abstract: 
Highly hydrophilic compounds such as nicotinamide metabolites are very difficult to separate via high-performance liquid chromatography (HPLC) using octadecyl (C18) columns. In general, for the separation of hydrophilic compounds, hydrophilic interaction liquid chromatography (HILIC) columns are used instead of reversed phase chromatography using C18 columns. However, HILIC columns generally obey complex separation mechanisms because ionic interactions are involved in the retention process, which hinders the optimization of the separation conditions. Additionally, the resulting peak shapes are disturbed when large amounts of aqueous samples are injected. This study demonstrates that COSMOSIL PBr columns, in which both hydrophobic and dispersive interactions occur, show high retention for various hydrophilic compounds under similar separation conditions as those used with C18 columns. Specifically, using a COSMOSIL PBr column, 11 nicotinamide metabolites could be separated under simpler conditions than those used previously with C18 columns, affording better peak shape for each compound. The applicability of the method was evaluated using a tomato sample, from which the nicotinamide metabolites were successfully separated. The results show that the COSMOSIL PBr column is a good alternative to the C18 column for a good separation of all the peaks, including impurity peaks.



The following products were used in this study.
COSMOSIL PBr Packed Column
#NMN #hilic #hplc #lcms #nicotinamide #reference

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Press Release: Separation of amyloid β fragment peptides using DL-Amino Acid Labeling Kit

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Press Release: ...
#Aminoacid #Chiral #amiroid #drug #hplc #peptide #pressrelease

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Separation of amyloid β fragment peptides with racemised and isomerised aspartic acid residues using an original chiral resolution labeling reagent

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Separation of a...
We are pleased to announce that the study using our DL-amino acid labeling kit, made in collaboration with Professor Hideaki Kakeya from Graduate School of Pharmaceutical Sciences, Kyoto University, was selected for inclusion in HOT Articles 2023 by the Royal Society of Chemistry journal Analyst, 2023, Advance Article


The following products were used in this study.
DL-Amino Acid Labeling Kit
#Aminoacid #DL #HPLC #Labeling #Reference #chiral

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Reference: Separation of long-stranded RNAs by RP-HPLC

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Reference: Separation of long-...
#dna #drug #hplc #mrna #reference #vaccine #widepore

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New Product: Protease Inhibitor Cocktail Tablets, EDTA-Free

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New Product: Protease Inhibito...
#newproduct #protease

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ASMS 2023: Booth# 418

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ASMS 2023 ASMS 2023
We are attending the ASMS 2023 Annual Conference, booth No. 418. June 4-8, Houston. TX
https://www.asms.org/
#Coreshell #Exhibition #HPLC #MS

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