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Nacalai USA's Blog

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  • ハッシュタグ「#lcms」の検索結果12件

Exciting new application alert! - COSMOSIL PYE

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Exciting new application alert!...
Exciting new application alert! We’ve just uploaded our latest analysis of #Thyroid #hormone using COSMOSIL PYE. Check out the application data below and let us know your thoughts!
 
Sample: Thyroid hormone
3,3’-Diiodo-L-thyronine (CAS#: 4604-41-5)
3,5-Diiodo-L-thyronine (CAS#: 1041-01-6)
3’,5’-Diiodo-L-thyronine (CAS#: 4192-14-7)
Levothyroxine [L-Thyroxine] (CAS#: 51-48-9)
3,3',5‐Triiodo‐L‐thyronine (CAS#: 6893-02-3)
3,3’,5’-Triiodo-L-thyronine (CAS#: 5817-39-0)
 
Column: COSMOSIL PYE
 
#Application #LCMS #clinical #coreshell #druganalyis #foodanalysis #isomer #pharma

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Just released: our newest analysis data! - Vanilline Isomers

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Just released: our newest ana...
#Application #druganalysis #foodanalysis #hplc #lcms

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Our latest analysis is now available! : Testosterone metabolites

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Our latest analysis is now avai...
#Application #LCMS #clinical #druganalysis #pharma

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Exciting new application alert! - COSMOSIL 3πNAP

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Exciting new ap...
Exciting new application alert! We’ve just uploaded our latest analysis results using COSMOSIL 3πNAP. Check out the application data below and let us know your thoughts!
 
Sample: Grapefruit juice extract 
    1: 6', 7'-Dihydroxybergamottin
    2: Bergamottin
Column: COSMOSIL 3πNAP
#Application #LCMS #clinical #druganalyis #foodanalysis #pharma

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ASMS 2024 : Booth No. 260

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ASMS2024 at Anaheim, CA ASMS2024 at Anaheim, CA
We are attending the ASMS 2024 Annual Conference, booth No. 260. June 2-6, Anaheim, CA.
#analytical #asms #exhibition #hplc #lcms #mass

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New Application: Chiral Analysis of Naringenin by RP-HPLC

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Chiral Analysis of Naringenin b... Chiral Analysis of Naringenin by RP-HPLC
Analysis of racemic naringenin on columns with three different chiral stationary phases. Cosmosil CHiRAL B shows significant resolution of the enantiomers compared with CHiRAL A and C.  The chromatogram is here!
 
#DL #application #chiral #flavanone #hplc #lcms #racemic

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PITTCON 2024: Booth# 2924

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PITTCON 2024: Booth# 2924
We will be attending the PITTCON 2024, booth No. 2924, February 26-28, San Diego, CA.
#c18 #drug #exhibition #hplc #lcms

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* 20% OFF * Exclusive Online Discount on COSMOSIL Special Columns

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* 20% OFF * Exclusive Online ...
For a limited time, we are offering a special promotion on COSMOSIL Cholseter, PBr, PFP, piNAP, and PYE columns. You can now purchase 4.6 x 150 mm and 250 mm columns at a 20% discount from the listed price by using the promo code S2024.
 
 
 
 
 
 
 
*** PromoCode: S2024 ***
*** Valid until 07/31/2024 ***
 
 
The discount will be:
- applied only to the columns listed on our website.
- not available to overseas.
- cannot be combined with any other offer, promotion or discount.
#drug #hplc #iosmer #lcms #screening #specialoffer

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Simultaneous Separation and Identification of All Structural Isomers and Enantiomers of Aminobutyric Acid.

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Simultaneous Separation and Id...
#aminoacid #chiral #drug #hplc #isomer #labeling #lcms #reference

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Separation of highly hydrophilic nicotinamide metabolites using a COSMOSIL PBr column

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Separation of highly hydrophili...
We published "Separation of highly hydrophilic nicotinamide metabolites using a COSMOSIL PBr column" in MethodsX, 2023, 10. 102061.

DOI: https://doi.org/10.1016/j.mex.2023.102061

Abstract: 
Highly hydrophilic compounds such as nicotinamide metabolites are very difficult to separate via high-performance liquid chromatography (HPLC) using octadecyl (C18) columns. In general, for the separation of hydrophilic compounds, hydrophilic interaction liquid chromatography (HILIC) columns are used instead of reversed phase chromatography using C18 columns. However, HILIC columns generally obey complex separation mechanisms because ionic interactions are involved in the retention process, which hinders the optimization of the separation conditions. Additionally, the resulting peak shapes are disturbed when large amounts of aqueous samples are injected. This study demonstrates that COSMOSIL PBr columns, in which both hydrophobic and dispersive interactions occur, show high retention for various hydrophilic compounds under similar separation conditions as those used with C18 columns. Specifically, using a COSMOSIL PBr column, 11 nicotinamide metabolites could be separated under simpler conditions than those used previously with C18 columns, affording better peak shape for each compound. The applicability of the method was evaluated using a tomato sample, from which the nicotinamide metabolites were successfully separated. The results show that the COSMOSIL PBr column is a good alternative to the C18 column for a good separation of all the peaks, including impurity peaks.



The following products were used in this study.
COSMOSIL PBr Packed Column
#NMN #hilic #hplc #lcms #nicotinamide #reference

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