Taurine is a biologically significant molecule with a zwitterionic character, which makes it a difficult analysis target. COSMOSIL HILIC has a unique anion-exchange mechanism which allows strong retention of taurine with good peak shape. It is USP packing type L104, specified on the official monogra...

COSMOSIL Application, which includes more than 7,700 applications using COSMOSIL/COSMOCORE columns, is now usable by clicking the link below which is in Nacalai Tesque, Inc. The application is searchable by sample category, sample name, CAS No., column name and particle size.COSMOSIL Applicationhttp...

Comparison of Retention Behavior between Supercritical Fluid Chromatography and Normal-Phase High-Performance Liquid Chromatography with Various Stationary PhasesReference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650800/COSMOSIL SFC Columns:https://www.nacalaiusa.com/products/list/63/cosmosil-...

Due to the lack of retention on ODS columns, oligosaccharides have typically been analyzed on specialty sugar columns. We have successfully analyzed inulins using COSMOSIL Sugar-D, a specialty column for saccharide analysis, and PBr, a unique reversed-phase column for polar and non-polar analytes.Ab...

Data courtesy of Pfizer Inc. La Jolla, Californiahttps://www.nacalaiusa.com/products/view/507/cosmosil-sfc-column-series

Hydrophilic interaction chromatography (HILIC) is a popular technique to analyze very polar molecules. However, it is often difficult to develop a robust method.HILIC Columns: Disadvantages・　Extremely sensitive to sample solvent used resulting in shifting retention time.・　Small sample loading capaci...

Feb. 22nd Monday 7:00 PM Poster # 53--------------------------Topic: MetabolomicsSeparating Vitamin D2 D3, their 25-OH Metabolites and C-3 EpimersThe accuracy of current vitamin D measurements by immunoassays and LCMS has been questioned due to the overlapping LC peaks with identical m/z values epim...

Not getting enough separation or retention with your C18 column? Watch this tutorial to learn how to improve your analysis.More information on COSMOSIL Cholesterhttp://www.nacalaiusa.com/products/view/61/cosmosil-cholesterMore information on COSMOSIL PBrhttp://www.nacalaiusa.com/products/view/238/co...

New applications for drugs listed in the Japanese pharmacopeia, metabolites and foods have been added to our database.To see each application, click the link below and put an application No. (AP-****) into a box.http://www.nacalai.co.jp/cosmosil/data/csmosrchtop.cfm?&lc=EDrugs listed in the Japanese...